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Recent Publications

List of publications IMBB (2011-2023)


Baev V., Milev I., Naydenov M., Apostolova M., Minkov G., Minkov I., Yahubyan G. (2011) Implementation of a de novo genome-wide computational approach for updating Brachypodium miRNAs. Genomics. 97(5): 282-293. (IF 6.205)


Georgieva, B., Milev, I. Minkov, I., Dimitrova, I., Bradford, A.P., Baev, V. (2012) Characterization of the uterine leiomyoma microRNAome by deep sequencing. Genomics. 99: 275–281. (IF 6.205)


Benina M., Obata T., Mehterov N., Ivanov I., Petrov V., Toneva V., Fernie A.R., Gechev T.S. (2013) Comparative metabolomics of Haberlea rhodopensis, Thellungiella halophyla, and Arabidopsis thaliana exposed to low temperature and subsequent recovery. Frontiers in Plant Science. 4: 499. (IF 4.402)

Gechev T., Mehterov N., Denev I., Hille J. (2013) A simple and powerful approach for isolation of Arabidopsis mutants with increased tolerance to H2O2-induced cell death. Methods in Enzymology 527: 203-220. (IF 2.194)

Petrov V., Schippers J., Benina M., Minkov I., Mueller-Roeber B., Gechev T. (2013) In search for new players of the oxidative stress, network by phenotyping an Arabidopsis T-DNA mutant collection on reactive oxygen species-eliciting chemicals. Plant Omics Journal. 69(6): 46-54. (IF 1.14)

Qureshi M., Neerakkal S., Gechev T., Hille J. (2013) The zinc finger protein ZAT11 modulates paraquat-induced programmed cell death in Arabidopsis thaliana. Acta Physiologie Plantarum, 35(6):1863-1871. (IF 2.078)

Sablok G., Milev I., Minkov G., Minkov I., Varotto C., Yahubyan G., Baev V. (2013) isomiRex: web-based identification of microRNAs, isomiR variations and differential expression using next-generation sequencing datasets. FEBS Letters. 587(16): 2629-34. (IF 3.341)

Thuenemann EC., Lenzi P., Love A.J., Taliansky M., Bécares M., Zuñiga S., Enjuanes L., Zahmanova G., Minkov I.N., Matić S., Noris E., Meyers A., Hattingh A., Rybicki E.P., Kiselev O.I., Ravin N.V., Eldarov M.A., Skryabin K.G., Lomonossoff G.P. (2013) The use of transient expression systems for the rapid production of virus-like particles in plants. Currant Pharmaceutical Design, 19(31): 5564-73. (IF 2.575)


Baev V., Milev I., Naydenov M., Vachev T., Apostolova M., Mehterov N., Gozmanova M., Minkov G., Sablok G., Yahubyan G. (2014) Insight into small RNA abundance and expression in high- and low-temperature stress response using deep sequencing in Arabidopsis. Plant Physiology and Biochemistry. 84: 105-114. (IF 3.720)

Gechev T., Hille J., Woerdenbag H.J., Benina M., Mehterov N., Toneva V., Fernie A.R., Mueller-Roeber B. (2014) Natural products from resurrection plants: potential for medical applications. Biotechnology Advances 32: 1091-1101. (IF 13.597)

Ivanov I., Benina M., Petrov V., Gechev T., Toneva V. (2014) Metabolic responses of Gloxinia perennis to dehydration and rehydration. Comptes Rendus de L'Academie Bulgare des Sciences. 67: 1657-1662. (IF 0.219)

Ivanova D., Milev I., Vachev T., Baev V., Yahubyan G., Minkov G., Gozmanova M. (2014) Small RNA analysis of potato spindle tuber viroid infected Phelipanche ramosa. Plant Physiology and Biochemistry. 74: 276-282. (IF 3.720)

Ivanova, D., Vachev, T., Minkov, G., Yahubyan, G., Zahmanova G., Naimov, S., Gozmanova, M. (2014) Expression changes of MYB1 and aco genes upon potato spindle tuber viroid infection of Phelipanche ramosa L. Comptes rendus de l’Acade'mie bulgare des Sciences. 67(6): 809-814. (IF 0.219)


 Benina M., Ribero D.M., Gechev T., Mueller-Roeber B., Schippers J.H.M. (2015) A cell type-specific view on the translation of mRNAs from ROS-responsive genes upon paraquat treatment of Arabidopsis thaliana leaves. Plant Cell Environ. 38: 349-363. (IF 6.362)

Naydenov, M., Baev, V., Apostolova, E. Gospodinova, N., Gozmanova, M., Yahubyan G. (2015) High-temperature effect on genes engaged in DNA methylation and affected by DNA methylation in Arabidopsis. Plant Physiology and Biochemistry. 87(2): 102-108. (IF 3.720)

Petrov V., Hille J., Mueller-Roeber B., Gechev T. (2015) ROS-mediated abiotic stress-induced programmed cell death in plants. Frontiers in Plant Science 6: 69. (IF 4.409)

Sablok G., Srivastva A.K., Suprasanna P., Baev V., Ralph P.J. (2015) isomiRs: Increasing evidences of isomiRs complexity in plant stress functional biology. Frontiers in Plant Science. 6: 949. (IF 4.402)

Vachev T.I., Stoyanova V.K., Ivanov H.Y., Minkov I.N., Popov N.T. (2015) Investigation of Fasciculation and Elongation Protein ζ-1 (FEZ1) in Peripheral Blood Reveals Differences in Gene Expression in Patients with Schizophrenia. Balkan Journal of Medical Genetics. 18(1): 31-37. (IF 0.4)

Zahmanova G., Mazalovska M., Toneva V., Minkov I. Lomonossoff G. (2015) Production of chimeric virus-like particles bearing M2e influenza epitope in Nicotiana benthamiana plants. Journal of Biotechnology. 208(20): 109. (IF 3.163)


Kirov K., Krachunov M., Kulev O., Nisheva-Pavlova M., Minkov G., Vassilev D. (2016) Reducing false negatives for errors in SNP detection using a machine learning approach. Comptes Rendus de L'Academie Bulgare des Sciences. 69(7): 885-890. (IF 0.219)


Anachkov N., Yahubyan G., Minkov I., Charishnikova O., Popova T., Touraev A. (2017) Successful microspore reprogramming towards embryogenesis of Bulgarian pepper varieties and effects of stress treatments and wheat ovaries on embryo formation. Comptes Rendus de L'Academie Bulgare des Sciences, 70(5): 739-748. (IF 0.219)

Iliev, I., Yahubyan, G., Marhova, M., Apostolova, E., Gozmanova, M., Gecheva, G., Kostadinova, S., Ivanova, A., Baev, V. (2017) Metagenomic profiling of the microbial freshwater communities in two Bulgarian reservoirs. Journal of Basic Microbiology. 57(8): 669-679. (IF 1.909)

Ivanova, Z., Sablok, G., Daskalova, E., Zahmanova, G., Apostolova, E., Yahubyan, G. (2017) Baev, V. Chloroplast genome analysis of resurrection tertiary relict Haberlea rhodopensis highlights genes important for desiccation stress response. Frontiers in Plant Science. 204(8): 1-18. (IF 4.407)

Mazalovska, M., Varadinov, N., Koynarski, T., Minkov, I., Teoharov, P., Lomonossoff, G.P., Zahmanova, G. (2017) Detection of serum antibodies to Hepatitis E virus based on HEV genotype 3 ORF2 capsid protein expressed in Nicotiana benthamiana. Annals of Laboratory Medicine, 37(4): 313-319. (IF 2.803)


Gevrenova, R., Bardarov, K., Bouguet-Bonnet, S., Voynikov, Y., Balabanova, V., Zheleva-Dimitrova, D., Henry, M. (2018) A new liquid chromatography-high resolution Orbitrap mass spectrometry-based strategy to characterize Glucuronide Oleanane-type Triterpenoid Carboxylic Acid 3, 28-O-Bidesmosides (GOTCAB) saponins. A case study of Gypsophila glomerata Pall ex M. B. (Caryophyllaceae) Journal of Pharmaceutical and Biomedical Analysis, 159, pp. 567-581. IF 3.571

Durgud M., Gupta S., Ivanov I., Omidbakhshfard M.A., Benina M., Alseekh S., Staykov N., Hauenstein M., Dijkwel P.P., Hörtensteiner S., Toneva V., Brotman Y., Fernie A.R., Mueller-Roeber B., Gechev T.S. (2018) Molecular mechanisms preventing senescence in response to prolonged darkness in a desiccation-tolerant plant. Plant Physiology. 177(3): 1319-1338. (IF 6.305)3

Durgud M.R., Stoyanova V.K., Popov N.T., Minchev D., Ivanov H., Minkov I.N., Vachev T.I. (2018) Non-invasive prenatal sex identification using cell-free fetal DNA in maternal circulation. Comptes Rendus de L'Academie Bulgare des Sciences. 71(12): 1687-1693. (IF 0.219)

Minkov, G., Toneva, V., Ivanova, Z., Baev, V. (2018) LoopRNA – Java module for RNA structure annotation. Comptes Rendus de L'Academie Bulgare des Sciences. 71(9): 1215-1221. (IF 0.219)

Naydenov, M., Gospodinova, N., Apostolova, E., Anachkov, N., Baev, V., Gozmanova, M., Minkov, I., Yahubyan, G. (2018) Transposon-associated polymorphisms of stress-responsive gene promoters in selected accessions of Arabidopsis thaliana. Acta Biochimica Polonica. 65(3): 391-396. (IF 1.463)

Petrov, V., Qureshi, M.K., Hille, J., Gechev, T. (2018) Occurrence, biochemistry and biological effects of host-selective plant mycotoxins. Food and Chemical Toxicology. 112: 251-264. (IF 4.679)


Gupta S., Dong Y., Dijkwel P., Mueller-Roeber B., Gechev T. (2019) Genome-wide analysis of ROS antioxidant genes in resurrection species suggest an involvement of distinct ROS detoxification systems during desiccation. International Journal of Molecular Sciences. 20(12): 3101. (IF 4.183).

Dong, Y., Gupta, S., Sievers, R., Wargent, J.J., Wheeler, D., Putterill, J., Macknight, R., Gechev, T., Mueller-Roeber, B., Dijkwel, P.P. Genome draft of the Arabidopsis relative Pachycladon cheesemanii reveals novel strategies to tolerate New Zealand's high ultraviolet B radiation environment. BMC Genomics. 20(1):838, 2019. (IF 3.594)

Iliev I., Marhova M., Kostadinova S., Gochev V., Tsvetkova M., Ivanova A., Yahubyan G., Baev, V. Metagenomic analysis of the microbial community structure in protected wetlands in the Maritza River Basin. Biotechnology and Biotechnological Equipment, 33(1), 1721-1732, 2019. (IF 1.186)

Minchev D.S., Popov N.T., Naimov S.I., Minkov I.N., Vachev T.I. (2019) Comparative expression analysis of human endogenous retrovirus elements in peripheral blood of children with specific language impairment. Balkan Journal of Medical Genetics. 22(1): 49-56. (IF 0.4)

Nasar-Eddin, G.M., Simeonova, R.L., Zheleva-Dimitrova, D.Zh., Gevrenova, R.S., Savov, I.I., Bardarov, K.V., Danchev, N.D. Beneficial effects of Clinopodium vulgare water extract on spontaneously hypertensive rats. (2019) Bulgarian Chemical Communications, 51, 156-160. IF 0.398

Zheleva-Dimitrova, D., Simeonova, R., Gevrenova, R., Savov, Y., Balabanova, V., Nasar-Eddin, G., Bardarov, K., Danchev, N. In vivo toxicity assessment of Clinopodium vulgare L. water extract characterized by UHPLC-HRMS. (2019) Food and Chemical Toxicology, Dec;134:110841. doi: 10.1016/j.fct.2019.110841134, IF 5.572


Apostolova E., Gozmanova M., Nacheva L., Ivanova Z., Toneva V., Minkov I., Baev V., Yahubyan G. (2020) MicroRNA profiling the resurrection plant Haberlea rhodopensis unveils essential regulators of survival under severe drought. Biologia Plantarum. 64: 541-550. (IF 1.747)

Mardanova E.S., Takova K.H., Toneva V.T., Zahmanova G., Tsybalova L., Ravin N. (2020) A plant-based transient expression system for the rapid production of highly immunogenic Hepatitis E virus-like particles. Biotechnology Letters. 42(11): 2441-2446. (IF 2.461)

Takova K., Koynarski T., Minkov I., Ivanova, Z., Toneva V., Zahmanova G. (2020) Increasing Hepatitis E virus seroprevalence in domestic pigs and wild boar in Bulgaria. Animals. 10(9): 1521. (IF 2.752)

Zahmanova G., Mazalovska M., Takova K., Toneva V., Minkov I., Mardanova E., Ravin N., Lomonossoff G. (2020) Rapid high-yield transient expression of swine Hepatitis E ORF2 capsid proteins in Nicotiana benthamiana plants and production of chimeric Hepatitis E virus-like particles bearing the M2e influenza epitope. Plants. 9(1): 29. (IF 3.935).


Baev V., Ivanova Z., Yahubyan G., Toneva V., Apostolova E., Minkov G., Minkov I. (2021) Analysis of the complete mitochondrial genome sequence of the resurrection plant Haberlea rhodopensis. Acta Biochim. Pol. 68(2):277-286. (IF 2.149).

Staykov N., Angelov M., Petrov V., Minkov P., Kanojia A., Guinan K., Alseekh S., Fernie A., Neerakkal S., Gechev T.S. (2021) An Ascophyllum nodosum-derived biostimulant protects model and crop plants from oxidative stress. Metabolites. 11(1): 24. (IF 4.754).

Takova K., Koynarski T., Minkov G., Toneva V., Mardanova E., Ravin N., Lukov G.L., Zahmanova G. (2021) Development and Optimization of an Enzyme Immunoassay to Detect Serum Antibodies against the Hepatitis E Virus in Pigs, Using Plant-Derived ORF2 Recombinant Protein. Vaccines. 9(9): 991. (IF 4.422).

Zahmanova G., Mazalovska M., Takova K., Toneva V., Minkov I., Peyret H., Lomonossoff G. (2021) Efficient production of chimeric Hepatitis B virus-like particles bearing an epitope of Hepatitis E virus capsid by transient expression in Nicotiana benthamiana. Life. 11(1): 64. (IF 3.817)


Ivanova Z., Minkov G., Gisel A., Yahubyan G., Minkov I., Toneva V., Baev V. (2022). The Multiverse of Plant Small RNAs: How Can We Explore it? Int.J.Mol.Sci. 23(7): 3979. (IF 5.926)

Jung JW, Zahmanova G, Minkov I, Lomonossoff GP. (2022) Plant-based expression and characterization of SARS-CoV-2 virus-like particles presenting a native spike protein. Plant Biotechnology Journal, 13.26)

Zahmanova G., Takova K., Valkova R., Toneva V., Minkov I., Andonov A., Lukov G. (2022). Plant-Derived Recombinant Vaccines against Zoonotic Viruses. Life, 12(2), 156. (IF 3.817).


Baev, V.; Gisel, A.;Minkov, I. The FascinatingWorld of Plant Non-Coding RNAs. Int. J. Mol. Sci. 2023, 24, 10341.

Zahmanova, G.; Aljabali, A.A.; Takova, K.; Toneva, V.; Tambuwala, M.M.; Andonov, A.P.;Lukov, G.L.; Minkov, I. The Plant Viruses and Molecular Farming: How Beneficial They Might Be for Human and Animal Health? Int. J. Mol. Sci. 2023, 24, 1533.

Zahmanova, G.; Takova, K.; Tonova, V.; Koynarski, T.; Lukov, L.L.; Minkov, I.; Pishmisheva, M.; Kotsev, S.; Tsachev, I.; Baymakova, M.; et al. The Re-Emergence of Hepatitis E Virus in Europe and Vaccine Development. Viruses 2023, 15, 1558.